NEUROSCIENCE ENHANCEMENTS
PatchPilot™
Intelligent Automation for Patch Clamp Electrophysiology
Understanding the brain remains one of science’s greatest challenges. While neuroscience continues to advance, many of the techniques used to study neural function remain technically demanding, labour intensive and difficult to scale.
Bioptix develops intelligent technologies that help researchers overcome these challenges, enabling more efficient workflows, improved reproducibility and greater accessibility to advanced neuroscience techniques.
Why PatchPilot™
Patch clamp electrophysiology remains one of the most powerful techniques for studying neural function, but it is also one of the most technically demanding.
PatchPilot™ was developed to simplify key stages of the workflow through intelligent automation, enabling laboratories to improve consistency, reduce manual variability and make advanced electrophysiology more accessible.
Whether supporting experienced electrophysiologists or researchers new to the technique, PatchPilot™ helps laboratories spend less time managing technical complexity and more time generating meaningful scientific data
Key Benefits
- Improve experimental consistency
- Reduce technical barriers
- Increase workflow efficiency
- Support reproducible research
- Reduce reliance on highly specialised manual techniques.
- Maintain researcher control throughout the experiment
Key Features
PatchPilot™ combines precision automation with flexible workflow control, allowing researchers to integrate automation where it adds the greatest value.
Automated Pipette Positioning
Supports accurate and repeatable pipette placement through precision manipulator control.
Automated Pressure Control
Provides consistent pressure management throughout critical stages of the recording process.
Automated Seal Formation
Improves workflow consistency by automating one of the most technically demanding stages of patch clamp electrophysiology.
Automated Break-In
Supports reliable transition to whole-cell recording.
Flexible Workflow Control
Operate in automated or semi-automated modes, allowing researchers to determine the level of automation best suited to their workflow.
Researcher-Led Cell Selection
PatchPilot™ preserves scientific judgement by allowing researchers to identify and select target cells while the system manages the precision mechanics required to establish recordings.
Guided Workflow
PatchPilot™ supports researchers through a structured workflow that combines automation with user oversight.
From sample preparation and system calibration through to pipette positioning, seal formation and data acquisition, each stage is designed to improve consistency while maintaining flexibility.
Integrated quality checks help support reliable experimental outcomes, with automated recovery processes assisting where predefined criteria are not achieved.
Designed for the Future
PatchPilot™ is the first technology within the Bioptix platform.
Future development will continue to expand its capabilities, with planned enhancements including support for Multi-Patch electrophysiology and Patch-seq integration as part of Bioptix’s long-term vision for a more connected neuroscience research ecosystem.
| Specification | Details |
|---|---|
| Application | Whole-cell patch clamp in acute brain slices |
| Recording Modes | Automated, Semi-Automated, Manual |
| Cell Selection | Researcher-Led |
| Pipette Positioning | Automated |
| Pressure Control | Integrated |
| Seal Formation | Automated |
| Break-In | Automated |
| Data Acquisition | HEKA Integration |
| Amplifier | HEKA EPC 10 USB |
| Imaging Compatibility | SliceScope Pro |
| Control Software | NeuroPilot OS™ |
Learn More About PatchPilot™
Whether you’re evaluating automated electrophysiology for the first time or looking to improve the efficiency and reproducibility of your existing workflows, our team is here to help.